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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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  • Cialis (tadalafil) can alter the levels of tadalafil in your blood by inhibiting its phosphodiesterase type 5 (PDE5) enzyme. This can result in a lower blood pressure level when used with tadalafil. Avoid using Cialis while taking tadalafil.
  • Cialis (tadalafil) may increase the blood pressure by interfering with its metabolism by enhancing the blood pressure-lowering effects of the medication, which can cause symptoms like dizziness or dizziness. Limiting tadalafil consumption is recommended while using tadalafil.
  • Alpha-blockers (such as prazosin, terazosin, tamsulosin) can improve blood pressure-lowering effects of tadalafil, but this should be done under a doctor's guidance.
  • enalapril or lisinopril can improve blood pressure-lowering effects of tadalafil, but this may not be guaranteed when taken with other medications that may cause heartburn.
  • Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

    Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

    Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

    If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

    For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

    • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
    • Your doctor may recommend taking generic Cialis regularly, once a day.

    Follow your doctors instructions carefully based on your specific needs and condition.

    If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

    Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

    irlwindsinsonertDoes Tadalafil work for you?

    Tadalafil citrate may not be as effective as previously thought. Because of this, we keep in mind that this drug might cause your urinary tract to get wider during sexual activity (and sometimes even BPH). We don't recommend this treatment if you have:

    • Urethral or pelvic pain or symptoms of infections
    • Allergic reactions (such as difficulty urinating or sudden changes in urination)
    • Heart problems or a history of stroke or blood pressure issues
    • Low or high blood pressure
    • Peyronie's disease or recurrent urinary tract infections
    • BPH characterized by prolonged erections
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    Unlike other medications tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by blocking the action of an enzyme called PDE6. This prevents the smooth muscle tissue in your penis from relaxing and allowing more blood to flow into them.

    While Tadalafil is effective for treating erectile dysfunction, it does not work for everyone. If you have characteristics of BPH or erectile dysfunction, please talk to your healthcare provider about having PDE5 inhibitor medications applied to your home.

    Some BPH treatments have the potential to affect both men and women. This is because BPH causes prostate enlargement in both men and women. If you had BPH and cannot take generic tadalafil, you may have options:

    • A prescription ED treatment like Viagra
    • A lifestyle medication like Diflucan
    • An ED treatment like Viagra
    • A ED treatment like Cialis

    If you take generic tadalafil and experience side effects, seek medical attention immediately. Prolonged and possibly dangerous treatment has been shown to increase the risk of Viagra's side effects.

    Vidalista

    Unlike generic tadalafil, which may cause you to feel blue after sexual activity,idalis does not cause sudden vision loss. It is a phosphodiesterase type 5 (PDE5) inhibitor. This prevents smooth muscle cells in your penis with long-term sexual activity from relaxing and allowing more blood to flow into them. This results in an erection during sexual stimulation.

    Although Vidalista is generally well-tolerated, side effects can occur.

    Before taking Cialis, tell your doctor and pharmacist if you are allergic to Cialis, any other medications, or any of the ingredients in Cialis.

    Before taking Cialis, tell your doctor and pharmacist about all the products you use, including prescription and over-the-counter drugs, vitamins, and herbal products. Cialis may interact with certain other medications, including nitrates (e.g., nitroglycerin) and certain alpha-blockers (e.g., doxazosin). Discuss all the products you use including street drugs, supermarket and health food products, and natural supplements. Cialis may alter the results of certain hormonal medications.

    Cialis should be used only when needed, as it may cause serious side effects such as vision problems, priapism (a prolonged and painful erection), and priapism (a prolonged and painful erection that does not go away; an erection that lasts more than 4 hours). If you are taking Cialis, it is important to tell your doctor and pharmacist before taking it that you are using this medication. Cialis may cause dizziness or lightheadedness in some people. If you experience any of the following symptoms, call your doctor immediately: fainting, chest pain, rapid heartbeat, shortness of breath, and/or nausea. Do not drive or do anything that requires your mental alertness to know you are having a medical emergency.

    Before taking Cialis, tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and herbal products, and any other supplements you are taking.

    Cialis may cause side effects. However, they are usually mild and temporary. Side effects tend to subside once the medication has been stopped. However, many people who experience side effects stop the medication after a few days.

    Tell your doctor if you are pregnant or planning to become pregnant. Cialis may harm an unborn baby. Tell your doctor right away if you have any of the following side effects: changes in sex drive; changes in erection firmness; sudden decreased or loss of hearing; numbness or weakness in your limbs; pain, fever, and swelling in your arms, legs, or lower legs; pain, sore throat, and/or swelling in your feet or hands; a severe headache; a stiff neck, especially for the first six months or longer; vision problems such as decreased vision or sudden vision loss; a prolonged and painful erection (priapism), a painful or prolonged erection (an erection that lasts longer than 4 hours), or a sudden, severe, persistent erection (priapism) that lasts more than 4 hours (priapism).

    Cialis may cause side effects not listed in this medication guide. If you have a known side effect, talk to your doctor or pharmacist about whether you can take Cialis. If you are taking Cialis and experience any side effects, such as dizziness, headache, stomach upset, indigestion, or diarrhea, stop taking Cialis and call your doctor immediately.

    As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours.

    Most common Tadalafil side effects

    • Headache
    • Indigestion
    • Back pain
    • Muscle pain
    • Flushing
    • Stuffy nose

    Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

    • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
    • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
    • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness.

    For a complete list of possible side effects,.

    Possible drug interactions

    Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

    On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

    For a complete list of possible drug interactions,.

    Other important safety information

    Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

    After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

    Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

    Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Dosage and direction

    Warnings

    Tadalafil (Cialis) is intended to be used at a dose of 5 milligrams (mg) Tadalafil is not recommended for patients who have experienced side effects with Tadalafil (Cialis).

    Contraindications

    Tadalafil (Cialis) is contraindicated in patients with heart problems, high blood pressure, or uncontrolled high cholesterol levels.

    Pregnancy and breast feeding

    The safety and efficacy of Tadalafil (Cialis) in pregnancy have not been studied in healthy female patients.

    Interactions

    Tadalafil (Cialis) can interact with other medications. Patients should inform their doctor of all medications or supplements they are taking.